We have been focused on producing antibodies for scientific research and development. Performance is guaranteed for the applications stated in datasheets. Our antibodies are widely used in many kinds of protein purification and detections.
PROTACs (PROteolysis TArgeting Chimeras) are heterobifunctional small molecules containing binding moieties for an E3 ubiquitin ligase and a target protein joined by a linker. PROTACs induce targeted protein degradation via the ubiquitin proteasome system. The binding of both moieties results in the formation of a ternary complex between target protein and E3 ligase, leading to polyubiquitination of the target protein, its recognition by the proteasome and subsequent degradation. A key feature of PROTACs is their catalytic mode of action. They dissociate following ubiquitination and rebind to new target proteins, which allows their use at sub-stoichiometric concentrations.
We provide reagents and other consumables in protein assay and other molecular biological experiments, including protein extraction, analysis and detection.
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